Iron rusts from disuse; water loses its purity from stagnation. Even so does inaction sap the vigor of the mind.
Leonardo offers something subtler than the tired "use it or lose it" advice—he's saying that *nothing* remains neutral under inaction. Iron doesn't simply sit still; it *actively* corrodes. Water doesn't wait; it *becomes* something harmful. The mind, then, isn't like a muscle that atrophies from neglect, but more like a living system that actively degenerates into something worse than merely weak—it can rust into bitterness or stagnate into confusion. When someone spends years in a job that demands nothing of them, they often don't plateau at their current abilities; they frequently find their judgment clouded, their curiosity sharpened into anxiety, their confidence curdled into cynicism. The quote warns not just against laziness, but against the peculiar damage of being *unchanged*—as if the mind itself becomes toxic to itself without friction.